IFNG and melanoma: We did not identify any expressed alterations in the B2M, HLA-A, -B or -C genes in the transcriptome data from the 79 melanoma biopsies, and the mutations identified in other genes associated with antigen presentation and IFNγ signaling (i.e., JAK1, JAK2, STAT1, STAT2, IFNGR1, IFNGR2, TAP1, TAP2) were not exclusively identified in poor responders or PROG biopsies (Supplementary Data 3).