ITGA1 and ovarian carcinoma: Interestingly, DDR2 knockdown significantly abrogated COL11A1-induced FASN overexpression (Fig. 4B) while ITGA1 knockdown only slightly reduced FASN expression (data not shown), suggesting that DDR2 might be the predominant receptor that mediates COL11A1-induced FASN expression in ovarian cancer cells.