In accordance with these reports, we demonstrated that TAM secrete higher amounts of TGFBI compared to other cell populations in the ascites, e.g., tumor cells or TATs (Fig. 3), and that TGFBI in the TAM secretome enhances tumor migration proven by neutralizing antibodies (Fig. 6) and RNA silencing (Fig. 7). The gene discussed is TGFBI; the disease is neoplasm.