Notably, while the numbers of CD11b+ DCs, Ly6Chi and Ly6Clo monocytes, F4/80hi CD11blo macrophages and eosinophils were significantly greater in STAT1/RAG1 DKO mice when compared with STAT1 KO mice, the numbers of mature and immature neutrophils and immature granulocytes were significantly greater in STAT1 KO mice than in STAT1/RAG1 DKO mice following infection. The gene discussed is ITGAM; the disease is infection.