Using this strategy, we previously identified two mRNA based biomarkers, ULBP2 and SEMA5A, for the prognostication of colon cancer [42]; and identified an independent gene panel for prediction of prognosis in both diffuse and intestinal type gastric cancer (unpublished data); which shows that the growing transcriptomic data enables discovery of such biomarkers which could have been missed when less patients studied. Here, ULBP2 is linked to malignant colon neoplasm.