AMH and polycystic ovary syndrome: Daughters born to mothers with PCOS have a 5-fold increased risk of developing PCOS themselves (9, 10, 18) and, as newborn infants, exhibit elongated anogenital distance (AGD) (19) and facial sebum (20), with elevated circulating levels of ovarian AMH (21, 22) indicative of exaggerated antral follicle numbers.