MiR‐125a was negatively associated with Scr (r = −.261, P < .001), WBC (r = −.184, P = .010), CRP (r = −.412, P < .001), TNF‐α (r = −.387, P < .001), IL‐1β (r = −.402, P < .001), IL‐6 (r = −.309, P < .001), and IL‐8 (r = −.316, P < .001), while positively correlated with albumin (r = .398, P < .001) in sepsis patients. This evidence concerns the gene CXCL8 and Sepsis.