HAVCR1 and acute kidney injury: As figure 5 shows, the urinary KIM-1 level in children with stage 2-3 AKI were higher than non-AKI children within the first 12 hours (SMD = 0.84; 95% CI: 0.35 to 1.33; p = 0.001), 24-12 hours (SMD = 1.02; 95% CI: 0.31 to 1.73; p = 0.005) and 96-24 hours (SMD = 0.75; 95% CI: 0.27 to 1.22; p = 0.002) after admission.