While BNP (brain natriuretic peptide) and NT-proBNP (N-terminal-proBNP) are more likely to predict heart failure and are associated with increased all-cause mortality, troponins have demonstrated their impact in detecting patients prone to acute myocardial infarction among those at high-risk for coronary artery disease (because of cancer treatment)58. This evidence concerns the gene NPPB and heart failure.