Erythrocyte membrane pump Increased sodium-lithium countertransport activity Thiol protein alkylation with N-ethtyl maleimide (NEM) is one of the mechanisms for SLC impairment in T2DM A good predictor of hypertension A useful biomarker for early detection of nephropathy in type 2 diabetes. Here, CCL21 is linked to type 2 diabetes mellitus.