induce apoptosis by targeting BCL2; induce the apoptosis of rat activated pancreatic stellate cells by targeting Bcl-2 in vitro; modulate multidrug resistance by targeting BCL2 in human gastric cancer cells; inhibits glioma cell growth and invasion through suppression of BCL2 and the nuclear factor-κB1/MMP9 signaling pathway. This evidence concerns the gene MMP9 and gastric cancer.