AQP7 and hypertensive disorder: Table 5 shows the results after adjustment for age, gender, duration of hypertension, family history of hypertension, family history of stroke, SBP, TC, TG, and FBG. Individuals with the CTA haplotype in AQP7 have a higher risk of stroke compared to those with the highest frequency of single-body CCG (P < 0.05). As shown in Table 6, the analysis of AQP9 by SNPstats found that there was no statistically significant difference in the risk of stroke between individuals with the highest frequency of haplotype CC and those with the remaining haplotypes (P > 0.05).