The positive rate and high expression rate of BMPER in ovarian epithelial malignant tumors were 90.43% and 73.91%, respectively, which were significantly higher than the corresponding values in ovarian epithelial borderline tumors (73.91%, 39.13%), ovarian epithelial benign tumors (41.67%, 16.67%), and normal ovarian tissue (30.00%, 10.00%) (P < 0.01). This evidence concerns the gene BMPER and malignant epithelial tumor of ovary.