By ELISA, AIH-1-specific anti-F-actin were more frequent in patients with MS compared to NCs (21/133, 15.8% vs 7/150, 4.7%, p = 0.0017) (all but three of them were tested positive for the SMA-VG pattern by IIF, amongst them 3 patients were also positive for SMA-F pattern by IIF); anti-ssDNA in 13 (9.77%) MS compared to 5 (3.33%) % NCs (p = ns); and anti-dsDNA in 3 (2.3%) MS patients compared to 2 (1.33%) NCs (p = ns), all three were also positive for anti-ssDNA. The gene discussed is SMN1; the disease is myeloid sarcoma.