Excluding 4 cases with known MS and concomitant AILDs, 7 had shown positivity PBC-associated autoantibodies such as anti-AMA BPO, PBC-specific ANA anti-gp210, anti-PML and one has shown AIH-2 anti-LKM1 (anti-CYP2D6) abs. The gene discussed is NUP210; the disease is primary biliary cholangitis.