As one member of the UDP-N-acetyl-α-d-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T or GALNT) family, GALNT7 acts as a glycosyltransferase in protein O-GlcNAcylatio, regulating the interaction between cancer cells and the extracellular environment [22–24]. The gene discussed is GALNT7; the disease is cancer.