Other previous studies showed that TA could suppress UVB-induced melanocyte activation by decreasing the levels of prohormone convertase-2 and α-MSH 30, and TA inhibited melanogenesis by activating the autophagy system in cultured melanoma cells 31, suggesting that TA can affect melanocyte function in other multiple pathways without traditional inhibition of plasmin. Here, STAMBP is linked to melanoma.