RUNX3 was referred by other groups to mediate the epithelial‐mesenchymal transition induced by TGF‐β and play a part in the stem cell–like traits induced by aberrantly activated Wnt signalling in gastric cancer35 and to reduce cancer stem cells in hepatocellular carcinoma by suppressing Jagged1‐Notch signalling.36 Here, JAG1 is linked to cancer.