SOX8 and neoplasm: Moreover SCC25 xenografts with GOLPH3 knockdown grew slowly with regards to tumor weight and size compared with those in control as well as SOX8‐overexpression group (Figure 5B), but xenografts with SOX8 over‐expression and GOLPH3 knockdown showed fast growth with regards to tumor weight and size, relative to those showing knockdown of GOLPH3, together with those under control vector treatment (Figure 5B and C).