S100A4 and thyroid gland carcinoma: As the most widely studied putative receptor, the interaction of receptor for advanced glycation end‐products (RAGE) and S100A4 has an obvious effect on cell movement and are capable of modulating the motility of thyroid cancer cells, colon adenocarcinoma cells and vascular smooth muscle cells by regulating mitogen‐activated protein kinase/extracellular signal‐regulated kinase (MAPK/ERK) pathway and hypoxia signalling.40, 41, 42