Our LINC00152 silencing experiments suggest that disturbance of TP53 signalling pathway can also be involved in increased apoptosis rate and reduced cyclin D1 expression caused by LINC00152 knockdown, as – among others – PERP TP53 apoptosis effector gene was found to be up-regulated in LINC00152-silenced CRC cells. The gene discussed is PERP; the disease is colorectal carcinoma.