Parallel RNA expression (HTA2.0, GSE100179 [22]) and DNA methylation data (bisulfite pyrosequencing) from the same sample set containing 11 normal, 13 adenoma and 9 CRC biopsies revealed strong negative correlation between DNA methylation and expression of LINC00152 showing overexpression and hypomethylation in CRC (r=-0.8976, r2 = 0.8056) (Fig. 2D). The gene discussed is CYTOR; the disease is colorectal carcinoma.