CRP and alkaline phosphatase measurement: The methods of risk stratification and prediction of severity in the early period of AP have been developed over the decades, including several clinical scoring systems and laboratory parameters, such as the Acute Physiology and Chronic Health Examination (APACHE II) [4, 5], systemic inflammatory response Syndrome (SIRS) [6, 7], blood urea nitrogen (BUN) [8–10], creatinine [11], hematocrit [10], serum calcium [9], procalcitonin [12], C-reactive protein (CRP) [13] and base excess (BE) [9, 14].