INS and type 2 diabetes mellitus: Considering the findings that both low and high HbA1c values were associated with increased mortality and cardiac events [7], we recommend to follow current guidelines on T2DM in older persons proposing a defined target range of HbA1c levels (7.5–8.5%) [1, 3]; however, hypothesized positive effects of conservative insulin use and defined HbA1c target ranges are to be evaluated in future rigorous research.