Flow cytometry revealed that most cancer cells accumulated in the G2/M phase in HCT116 cells treated with hnRNP A0 siRNA (G1, 6.33%; G2/M, 68.29%; S, 25.38%), which was quite different from the status when they were treated with scrambled RNA (G1, 38.42%; G2/M, 26.83%; S, 34.75%) (Fig. 2a). This evidence concerns the gene HNRNPA0 and cancer.