SQSTM1 and lysosomal storage disease: Cellular autophagy is impaired in lysosomal storage diseases (Lieberman et al., 2012, Maetzel et al., 2014, Soga et al., 2015), thus here, we investigated the autophagy pathway in NSCs treated with the hit compounds, focusing on autophagy markers such as microtubule-associated protein 1 light chain 3-II (LC3-II) and the insoluble p62/SQSTM1 (p62).