SQSTM1 and GM1 gangliosidosis: Surprisingly, both markers were not enhanced in GM1 gangliosidosis-derived NSCs compared with normal cells (Figures 4F and S4D); however, treatment with amodiaquine and thiethylperazine enhanced the expression of LC3-II and reduced insoluble p62 in both normal and GM1 NSCs (Figures 4F and S4D).