The results showed that a significant positive correlation existed between the expression of ERP27, PDIA5, TXNDC12, ERP44, TXNDC5, P4HB, PDIA4, PDIA6, TMX1, TMX3 and DNAJC10 in gliomas, whereas the expression of all these genes was negatively correlated with CASQ1 and PDIA2 (Figure 3A). This evidence concerns the gene PDIA2 and central nervous system cancer.