The results showed that a significant positive correlation existed between the expression of ERP27, PDIA5, TXNDC12, ERP44, TXNDC5, P4HB, PDIA4, PDIA6, TMX1, TMX3 and DNAJC10 in gliomas, whereas the expression of all these genes was negatively correlated with CASQ1 and PDIA2 (Figure 3A). The gene discussed is PDIA6; the disease is central nervous system cancer.