PRMT5 regulates a broad range of physiological and cancer‐associated processes, such as DNA damage response, apoptosis control, EMT and inflammation, and is involved in the inhibition of tumour suppressors, including RB proteins, p53, programmed cell death 4 (PDCD4) and activation of survival pathways such as PI3K/AKT axis26, 27, 28, 29. This evidence concerns the gene PRMT5 and neoplasm.