FGF2 and chronic obstructive pulmonary disease: These could include (1) FGF2 expression patterns in the presence of acute and chronic inflammation status; (2) the interaction of FGF2 with typical immune cell types in asthma and COPD; (3) role of FGF2 in modulating the function of airway structural cells in airway remodeling, inflammation, and lung function; (4) role of FGF2 in in vivo disease models with acute or chronic inflammation; and (5) clinical studies in asthma and COPD patients with varying disease severity.