On the other hand, the potential breast cancer susceptibility gene in the FA pathway, FANCM, is also needed for recruiting CtIP (C-terminal binding protein interacting protein) and MRN (MRE11-RAD50-NBS1) at the site of ICL, during the HR process (Daley et al., 2013). This evidence concerns the gene RBBP8 and Friedreich ataxia.