Meanwhile, colorectal cancer (CRC) cell growth and colony formation were also inhibited by the induction of cell cycle G0/G1 arrest and apoptosis [10], increasing casp9 mRNA and pho-Casp9 protein and decreasing extracellular-regulated protein kinases (ERK), Casp3 mRNA, p-Akt, p-ERK, and pho-Casp3 proteins [11]. This evidence concerns the gene CASP9 and colorectal cancer.