From the results of two-tailed student’s t-tests for GSE10667 and GSE70866, the expression levels of all hub genes (COL3A1, COL1A2, OGN, COL15A1, ASPN, and MXRA5) were significantly higher in IPF tissues (Figure 5). The gene discussed is COL15A1; the disease is idiopathic pulmonary fibrosis.