As shown in Supplementary Table S2, IPF samples in COL3A1 high expression group were most significantly enriched in cellular adhesion molecules; IPF samples in COL1A2, OGN, COL15A1, ASPN, and MXRA5 high expression groups were most significantly enriched in ECM receptor interaction (Supplementary Tables S2–S7). The gene discussed is ASPN; the disease is idiopathic pulmonary fibrosis.