A total of 15 genes were identified to be significantly deregulated among 12 tumor types while the top 500 most differential genes of every tumor type were selected, including NCAPG, ASF1B, BIRC5, CCNB1, CDC20, CENPF, FOXM1, KIAA0101, KIF20A, PBK, PTTG1, RRM2, TK1, TPX2, UBE2C (Figure 1A, Supplementary Figure 1). The gene discussed is CENPF; the disease is neoplasm.