CACNA1A and spinocerebellar ataxia type 6: Accordingly, qRT-PCR analysis of post-mortem cerebellar samples from SCA6 patients revealed a significant decrease in the expression of BDNF transcripts (Takahashi et al., 2012), and an impairment in synaptic elimination of weaker CFs in the Cav2.1[84Q] SCA6 mouse model (Jayabal et al., 2017).