In this in vitro study, Vincristine and Doxorubicin chemoresistant subpopulations were identified as cells expressing the markers MYOD1 and NOG in two patient-derived soft-tissue tumor models (A-204, a rhabdoid tumor cell line, and RD, an embryonal rhabdomyosarcoma cell line). The gene discussed is MYOD1; the disease is rhabdoid tumor.