BRCA1 and breast cancer: In a recent study looking at 128 breast cancer patients in Korea with a BRCA1 or BRCA2 carriers, only 8 chose to undergo contralateral prophylactic mastectomies28.Among French-Canadians of Quebec who carry BRCA1 or BRCA2 variants, preventive options including bilateral prophylactic mastectomies are less popular than in other regions of Canada29, with only 8% of Quebec women heterozygous for a pathogenic variant opting for the surgery compared to 22–46% in other regions of Canada.