STIM1 and cerebrovascular disorder: Serum was pooled from six animals each, representing the following groups: 16-week-old SHR-A3 without salt loading; 28-week-old salt-loaded SHR-A3(Stim1-B2); and salt-loaded SHR-A3 animals at collected at 28 weeks of age (n = 2) or at euthanasia due to salt loading-induced cerebrovascular disease (n = 4).