ADH1B and breast cancer: In terms of the rs1229984 variant of the ADH1B gene, those homozygous for TT exhibited a significantly increased risk of breast cancer in both ever drinkers and those who daily consumed >12 g day alcohol (OR = 1.58, 95% CI = 1.15–2.17, P-value = 0.005; OR = 2.97, 95% CI = 1.49–5.94, P-value = 0.002); however, in women with a TC or CC genotype, no association was observed between alcohol consumption and breast cancer.