To further evaluate the potential antitumor effect of PD-L1 antibody in vivo, mice inoculated with Pan02-pLV-FOXP3 tumor cells were treated with anti-PD-L1 antibody or control IgG (200 μg, intraperitoneal injection q3d) for 3 weeks (Fig. 4a) when the tumor volume reached approximately 70 mm3. The gene discussed is FOXP3; the disease is neoplasm.