Mice inoculated with Pan02-pLV-FOXP3 cells were treated with PD-L1 and/or CCL-5 blocking antibodies (200 μg, intraperitoneal injection q3d) for 3 weeks, and when the tumor volumes reached approximately 70 mm3 (Fig. 6a), the effects of single or combined treatment on tumor growth were evaluated. The gene discussed is CD274; the disease is neoplasm.