One report showed that IL-17-producing CD4 T cells (ie, Th17 cells), but not IL-17-producing CD8 T cells (ie, Tc17 cells), were increased in the VAT of obese patients with diabetes when compared with the VAT of both non-diabetic obese and lean subjects.17 However, most of the reports lack a proper control group, that is, the VAT of lean healthy donors, and rarely stratify the obese population in dysglycemic and normoglycemic subjects. The gene discussed is CD8A; the disease is diabetes mellitus.