THBS1 and isolated hemihyperplasia: Furthermore, post hoc Newman–Keuls’s test indicated that the mRNA levels of TGF-β and TSP-1 were both elevated in the IH group when compared with control group (P < 0.05, Fig. 6c and d), and TUDCA could reduce the expression of these mRNAs (P < 0.05, Fig. 6c and d).