Common driver oncogenes and biomarkers in the tumor were negative for mutations in the gene encoding epidermal growth factor receptor (EGFR)/v-raf murine sarcoma viral oncogene homolog B1 (BRAF) or rearrangements in the anaplastic lymphoma kinase (ALK)/c-ros oncogene 1 (ROS1)/rearranged during transfection proto-oncogene (RET) genes, or the expression of programmed death ligand (PD-L1). The gene discussed is BRAF; the disease is neoplasm.