SETD1A and schizophrenia: SETD1A (fixed mSNC in promoter), implicated in schizophrenia and developmental language impairment [49, 50], acts in collaboration with a histone chaperone to promote proliferation of neural progenitor cells through H3K4 trimethylation at the promoter of β-CATENIN, while its knockdown causes reduction in proliferative neural progenitor cells and an increase in cells at the cortical plate [40].