PRC1 and Primary microcephaly: Two chromatin regulators with mSNC in regulatory regions are present in these two ontology terms and are associated to neurodevelopmental disorders: KDM6A (mSNC in promoter), which associates to the H3K4 methyltransferase complex [27], and is mutated in patients with Kabuki syndrome [33]; and PHC1 (mSNC in promoter), a component of the repressive complex PRC1 [27], found in patients with primary microcephaly-11 [18].