To relate Ara h 2 and Ara h 6 IgE binding to functional effector cell activation following stimulation with allergen, we took the same 10 dual-sensitized individuals with peanut allergy as assessed in the Ara h 2 and Ara h 6 inhibition experiments and performed MAT assays against both Ara h 2 and Ara h 6 across a range of concentrations. Here, IGHE is linked to peanut allergic reaction.