Moreover, the 19 overlapping genes derived from hepatitis B and pathways in cancer were discovered (Fig. 3), such as PIK3CG, CDKN1B, PIK3CD, FOS, MAPK8, AKT1, MYC, MAPK1, CREBBP, JUN, BCL2, CCND1, PIK3CA, PTEN, CYCS, PIK3CB, EP300, JAK1, and GRB2. The gene discussed is JUN; the disease is hepatitis B virus infection.