HAVCR1 and congestive heart failure: Renal tubular damage is present in CHF patients due to tubulointerstitial injury by renal tissue hypoperfusion or due to a damaged glomerular filtration barrier.10, 11, 12 Studies have shown that higher levels of urinary tubular damage markers N‐acetyl‐β‐d‐glucosaminidase and kidney injury molecule (KIM)‐1 entailed poor prognosis in CHF independently of eGFR.4, 12 Therefore, markers of renal tubular damage may reflect another pathway for renal alterations in the milieu of the CRS.