Although precise role in steroid hormone metabolism is yet to be determined, the recent identification of specific genetic variants in 17β‐hydroxysteroid dehydrogenase type 13 (HSD17B13) adds further plausibility to our approach as this enzyme appears to protect from the development of chronic liver disease and hepatocellular carcinoma with several studies demonstrating increased expression in NAFLD add further plausibility to our approach.25, 26. This evidence concerns the gene HSD17B13 and metabolic dysfunction-associated steatotic liver disease.