Substitution of BRD4 with Pin1-binding-defective BRD4-T204A mutant reduces BRD4 stability, which attenuates BRD4-mediated gene expression and suppresses cell proliferation, migration, invasion, and tumor formation, suggesting the positive correlation of Pin1 function and BRD4 stability in gastric cancer cells (Hu et al., 2017). This evidence concerns the gene PIN1 and gastric cancer.