Pin1 interacts with Thr538-Pro of ΔNp63α and disrupts p63α-WWP1 interaction to inhibit the proteasomal degradation mediated by E3 ligase WWP1, promoting ΔNp63α-induced cell proliferation of human oral squamous cell carcinoma (Li et al., 2013). The gene discussed is WWP1; the disease is oral cavity squamous cell carcinoma.