Bone marrow mesenchymal stem cells (BM-MSCs) are implicated in the promotion of tumor angiogenesis in gastric cancer (GC) since SGC-7901 cells in both, in vitro and in vivo models, increases VEGF release from tumor cells by the activation ERK1/2 and p38 MAPK pathways, resulting in angiogenesis promotion (57). This evidence concerns the gene VEGFA and gastric cancer.