Moreover, gastric cancer-derived MSCs (GC-MSCs) are also able to promote angiogenesis when interact with BGC-823 and MKN-28 GC cell lines, inducing overexpression of pro-angiogenic factors, such as, VEGF, MIP-2, TGF-β1, IL-6, and IL-8 favoring tube formation (58). The gene discussed is CXCL8; the disease is gastric cancer.