Oxidative phosphorylation and spliceosome were among the first five terms in the KEGG enrichment analysis (Figure 7E), while metabolic reprogramming in colon cancer was among the top terms identified through the Wikipathway cancer enrichment analysis (Figure 7F), which was consistent with the enrichment results of the ChIRP–MS analysis which found that SNHG6 may play an important role in the metabolism of CRC. This evidence concerns the gene SNHG6 and malignant colon neoplasm.