Given that inhibition of LOXL2-governed buildup of collagenous matrix during liver fibrosis facilitates the arrival of CX3CR1+ Ly6Chi monocytes and their MoMF progenies in the vicinity of fibrous collagen fibers (Figure 4), we investigated whether this macrophage subset expresses MMPs that can potentially degrade collagen fibers. This evidence concerns the gene LOXL2 and Hepatic fibrosis.