Pretreated DHA or ARS could ameliorate oxidative stress in AKI mice by restoring malonyl dialdehyde (MDA), nitric oxide (NO), glutathione peroxidase (GSH), catalase (CAT), and superoxide dismutase (SOD) activity in the kidney (An Y. et al., 2017; Liu et al., 2019). The gene discussed is CAT; the disease is acute kidney injury.